Research Paper Advance Articles

Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice

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Figure 3. Pericyte count per capillary mm in the retinas of young untreated, vehicle-treated and MTK-treated old mice. The pericytes were visualized by NG2 labeling, and the capillaries were visualized by ColIV labeling. Capillary length was measured using ImageJ. (A) Pericyte count per capillary mm labeling in superficial retinal layers of young untreated, vehicle-treated and MTK-treated old mice and (B) representative NG2 (green) and ColIV (red) labeling in superficial retinal layers of young untreated mice. (C) Pericyte count per capillary mm in the deep retinal layers of young untreated, vehicle-treated and MTK-treated old mice and (D) representative NG2 and ColIV labeling in the deep retinal layers of young untreated mice. Scale bar = 100 µm. The data are represented as bar graphs and scatter plots ± SDs, n = 3–11. Two-way ANOVA (main factors: group and sex) followed by a Dunnett multiple comparison test.