Research Paper Advance Articles

Impaired renal transporter gene expression and uremic toxin excretion as aging hallmarks in cats with naturally occurring chronic kidney disease

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Figure 3. Uremic toxins in healthy senior cats. Healthy cats in cohort 1 were divided into two groups: those less than 12 years of age (YNG), and those aged 12 years or older (OLD). (AE) The box and bars indicate means and SEM. P-values from the Mann-Whitney test are presented as asterisks: *P < 0.05. (F, G) Spearman’s correlation analysis between cat’s age and log concentration of TMAO and IxS, respectively. P-value and correlation coefficient are indicated in the plot.