Research Paper Advance Articles

Figure 8. Arg-ii deficiency prevents age-associated decrease in type-I and type-II muscle fibers. Representative confocal images showing Type-I (A) and Type-IIA (B) fibers in the soleus of young and old wt and arg-ii^-/- (ko) male mice. DAPI (blue) is used to stain nuclei. Scale bar = 100 µm. The graphs present the percentage of Type-I (C) and Type-II (D) fibers over the total number of fibers in the image. (E) the graph shows the ratio of Type-I and Type-II fibers expressed as fold change (wt young group was taken as reference). One-way ANOVA test was applied. n = 3 mice per group. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 between the indicated groups.