Figure 5. Arg-ii-/- mice reveal decreased inflammatory markers in aging skeletal muscles. mRNA expression levels of inflammatory markers and cytokines analyzed by qRT-PCR in soleus and tibialis from male (A) and female (B) young and old wild type (wt) and arg-ii-/- (ko) mice. One-way ANOVA was applied. n = 4–7 mice per group. *p < 0.05, **p < 0.01, ***p < 0.001 between the groups.