Research Paper Volume 16, Issue 22 pp 13648—13661

Figure 1. Experimental flow chart. Hyperspectral imaging technology was utilized to extract spectral features from five designated positions, known as Regions of Interest (ROIs), within the augmented dataset. This dataset was developed through a manual process based on the MMSE. Spectral analysis was then applied to these ROIs. The diagram highlights the cropped region of the fundus image as the Region of Interest (ROI), with the sampling positions located above the temporal vascular arcade (S1 and S2), at the fovea (F), and below the temporal vascular arcade (I1 and I2).