Research Paper Advance Articles

DNA-methylation age and accelerated epigenetic aging in blood as a tumor marker for predicting breast cancer susceptibility

class="figure-viewer-img"

Figure 4. Women with a history of bilateral oophorectomy: distribution of DNAmAge/AgeAccelDiff/IEAA by BC status. (AgeAccelDiff, epigenetic age acceleration measured as departure of DNAmAge from chronologic age; IEAA, intrinsic epigenetic age acceleration as residuals adjusted for cell composition; BC, breast cancer; DNAmAge, DNA methylation–based marker of aging). (A) DNAmAge, (B) AgeAccelDiff, (C) IEAA.