Research Paper Advance Articles

Unveiling KLHL23 as a key immune regulator in hepatocellular carcinoma through integrated analysis

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Figure 6. The role of KLHL23 in the tumor microenvironment of LIHC. (A) Immune cell distribution in KLHL23 high expression LIHC patients. This panel presents a comprehensive analysis of immune cell distribution in the tumor microenvironment of each LIHC patient using data from the TCGA database. The visualization shows the diversity and prevalence of different immune cell types in different patient samples, providing insight into the immune landscape within LIHC tumors. (B) Differences in the various immune cell proportions between groups with high and low KLHL23 expression in LIHC. (Abbreviations: no: no significant difference; yes: significant difference). (C) KLHL23 expression associated with immune cells. This section illustrates the results of a comprehensive association analysis between KLHL23 expression levels and a wide range of immune cells within LIHC tumors.