Figure 6. Thermotherapy decreases hippocampal soluble Aβ42 in male mice. Average concentration of hippocampal soluble Aβ42 was determined by ELISA in male and female mice. C57BL/6 mice were used as a negative control as denoted by the segmented y-axis. A two-tailed t-test was used to determine thermotherapy effects within a sex and genotype. The number of animals is either inset or above the error bars on each bar graph. *p < 0.05.