Editorial Volume 16, Issue 19 pp 12670—12672

Figure 1. Integration of inflammaging biomarkers with organ function markers. This figure illustrates the interplay between biomarkers of inflammaging and markers of organ function. Inflammaging is characterized by chronic, low-grade inflammation and can be assessed using markers such as high-sensitivity C-reactive protein (hs-CRP), cytokines, cellular senescence indicators, oxidative stress, and immune profiles. Both modifiable (e.g., lifestyle, diet, smoking) and non-modifiable (e.g., genetics, sex, age) factors influence inflammaging, which contributes to age-related organ decline. Organ function is evaluated using biomarkers such as blood glucose, BMI, kidney function (eGFR), lung function (FVC/FEV1), and arterial blood pressure. The inclusion of cardiac biomarkers such as high-sensitivity cardiac troponin (hs-cTn) and natriuretic peptides (BNP, NT-proBNP) is crucial for assessing cardiovascular risk and dysfunction. These markers act as early indicators of subclinical cardiac damage and predictors of future cardiovascular events. Incorporating these cardiac biomarkers into preventive care enhances risk stratification and informs therapeutic strategies to address residual inflammatory risk, a key factor in cardiovascular disease.