A proteomics approach to study mouse long bones: examining baseline differences and mechanical loading-induced bone formation in young-adult and old mice

Christopher J. Chermside-Scabbo; John T. Shuster; Petra Erdmann-Gilmore; Eric Tycksen; Qiang Zhang; R. Reid Townsend; Matthew J. Silva

doi:doi:10.18632/aging.206131

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Research Paper Volume 16, Issue 19 pp 12726—12768

A proteomics approach to study mouse long bones: examining baseline differences and mechanical loading-induced bone formation in young-adult and old mice

Figure 7. Temporal map of PANTHER Reactome Pathways for proteomics loading experiment. (A) Loading-responsive protein lists for each age and day combination (up and down lists separate) were input to PANTHER to identify enriched pathways. (B) Reactome pathways were arranged temporarily for upregulated or downregulated protein enrichment at each day and age combination. Both upregulated and downregulated lists were enriched for pathways.