Research Paper Volume 16, Issue 19 pp 12726—12768
A proteomics approach to study mouse long bones: examining baseline differences and mechanical loading-induced bone formation in young-adult and old mice
Figure 6. Tibias from old mice had fewer protein-level changes following loading compared to young-adult mice. (A) Volcano plots for each day and age combination following the loading experiment. The total number of loading regulated proteins is shown above with the upregulated number in red and the downregulated number in blue. (B) Loading-related proteins were input into PANTHER to identify enriched PANTHER pathways. (C) Loading-related PANTHER pathways were temporally arranged.