Figure 1 — Single-cell sequencing technology to characterize stem T-cell subpopulations in acute T-lymphoblastic leukemia and the role of stem T-cells in the disease process

Research Paper|Volume 16, Issue 20|pp. 13117–13131

Single-cell sequencing technology to characterize stem T-cell subpopulations in acute T-lymphoblastic leukemia and the role of stem T-cells in the disease process

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Figure 1.Single-cell mapping of pre-T childhood leukemia. (A) UMAP downscaling plot for clustering and annotation of pre-T leukemia and healthy control bone marrow mononuclear cells. (B) Bubble plots of marker gene expression profiles used for cell subpopulations. (C) Heatmap of marker gene expression profiles used to annotate cell subpopulations. (D) Proportion of each cell subpopulation between the two groups. (E) Proportion of each cell subpopulation within all cells.