Research Paper Volume 16, Issue 19 pp 12866—12892

DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway

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Figure 4. FAM3D promotes the growth of CRC cells in vivo. (A) Photographs of nude mice after the administration of FAM3D KO or FAM3D-overexpressing LoVo cells for 19 days. (B) Excised tumors on Day 19. (C) The weights of excised tumors on Day 19. (D) The tumor volumes were calculated as length × width2 × 0.5 every 2–3 days. (E) The body weights of the nude mice were recorded every 2–3 days. *P < 0.05; **P < 0.01.