Research Paper Volume 16, Issue 19 pp 12866—12892
DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway
Figure 3. FAM3D promotes CRC cell proliferation, migration, and invasion in vitro. (A, B) Migration and invasion were detected by transwell assays in (A) LoVo and (B) HT29 cells. (C, D) Overexpression of FAM3D was confirmed by (C) RT-qPCR and (D) Western blot in LoVo cells. (E, F) Proliferation was detected after FAM3D overexpression. (G, H) Migration and invasion were detected after FAM3D overexpression. **P < 0.01, ***P < 0.001, ****P < 0.0001.