Figure 6. Profiling of somatic nucleotide variation for lung adenocarcinoma patients. (A) The waterfall plot showed that the high-risk group had a nucleotide variation rate of 95.93%. (B) The waterfall plot showed that the low-risk group had a nucleotide variation rate of 80.83%. (C) The bar plot showed that the risk score was critically increased in the high-mutation group than in the low-mutation group. (D) The box plot demonstrated that the risk score was critically increased in the high-mutation group than in the low-mutation group. (E) Tumor mutation burden (TMB) for lung adenocarcinoma patients. (F) The high-risk group had an increased TMB level as compared with the low-risk group. (G) The TMB levels were also positively correlated with the risk score. * represents P < 0.05, ** represents P < 0.01, *** represents P < 0.001.