Research Paper Volume 16, Issue 18 pp 12432—12442
Frailty and pre-frailty associated with long-term diminished physical performance and quality of life in breast cancer and hematopoietic cell transplant survivors
Figure 2. Increased senescent cell burden in frailty across the ages. (A) p16INK4a expression was stratified by fit and frail status in all groups (BC and HCT) and by (B) age (≤59 versus ≥60 years old). Expression was normalized to 18S. Values represent the median with 95% confidence interval. Students unpaired two-tailed t test. * p<0.05, ** p<0.01.