Research Paper Volume 16, Issue 18 pp 12593—12607
Study of the role of leukocyte telomere length-related lncRNA NBR2 in Alzheimer’s disease
Figure 1. Verification that leukocyte telomere length is correlated with Alzheimer's syndrome using Mendelian randomization. (A) MR analysis for LTL on AD. (B) Sensitivity verification using leave-one-out analysis. (C) Scatterplot representing the causal link between LTL and AD. The horizontal axis reflects the genetic effect of each SNP on LTL. The vertical axis reflects the genetic impact of each SNP on the risk of developing AD. (D) Heterogeneity was assessed by IVW and MR-Egger tests. (E) Distribution of IVs associated with the location of SNPs on chromosomes. (F) Sankey diagram of SNP → gene ← tissue type.