Research Paper Volume 16, Issue 18 pp 12559—12573
The joint protective function of live- and dead-Lactobacillus plantarum GKD7 on anterior cruciate ligament transection induces osteoarthritis
Figure 4. Therapeutic effects of GKD7 treatment evaluated by histopathology. (A) H&E and Safranin-O/Fast Green staining coronal images of articular cartilage from representative knee joints in each group (magnification 4x). Quantitative analyses of (B) Osteoarthritis Research Society International (OARSI) scores, (C) cartilage scores, and (D) synovium scores. The black arrows indicate the cartilage destruction. The red arrows indicate the synovial inflammation. Scale bar = 500 µm. *p < 0.05 versus controls; #p < 0.05 versus the OA group.