Research Paper Volume 16, Issue 17 pp 12335—12345
Treatment of tumor-associated macrophages with PD-1 monoclonal antibodies affects vascular generation in cervical cancer via the PD-1/IRE1α/SHP2/HIF1α signaling pathway
Figure 2. Impact of PD-1 monoclonal antibodies in TAMs on the PD-1/IRE1α/SHP2 signaling pathway. (A) Protein banding plots of t-SHP2, IL-6, PD-L1, XBP-1 and cathepsin K and relative protein expression statistics; (B) protein banding plots of IL-4 and IL-10 and relative protein expression statistics. GAPDH as a control protein. Data were expressed as mean±SD. *P<0.05; **P<0.01; nsP>0.05.