Research Paper Volume 16, Issue 17 pp 12335—12345
Treatment of tumor-associated macrophages with PD-1 monoclonal antibodies affects vascular generation in cervical cancer via the PD-1/IRE1α/SHP2/HIF1α signaling pathway
Figure 1. Impact of PD-1 monoclonal antibodies in TAMs on the progression of cervical cancer. (A) Graphical representation of tumor-bearing nude mice experimental results and statistical graph of tumor volume and weight; (B) H&E staining results graph and statistical graph of tumor slice area; (C) Western blot bands of t-SHP2, p-SHP2, PD-1, and PD-L1 and relative protein expression levels. GAPDH as a control protein. Data were expressed as mean±SD. **P<0.01; nsP>0.05.