Research Paper Volume 16, Issue 16 pp 12063—12072

Mechanistic study of PD-L1 regulation of metastatic proliferation in non-small cell lung cancer through modulation of IRE1α/XBP-1 signaling pathway in tumor-associated macrophages

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Figure 5. PD-L1 can regulate metastasis and proliferation of non-small cell lung cancer by modulating the IRE1α/XBP-1 signaling pathway in tumor-associated macrophages (schematic mechanism).