Research Paper Volume 16, Issue 16 pp 12063—12072

Mechanistic study of PD-L1 regulation of metastatic proliferation in non-small cell lung cancer through modulation of IRE1α/XBP-1 signaling pathway in tumor-associated macrophages

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Figure 2. Effect of nabulizumab and IRE1α inhibitor on protein metrics in different cells. (A) Protein indexes and statistics of P- IRE1α, XBP-1s, IL-6 in THP-1 cells in each group. (B) Protein indexes and statistics of P-STAT3, PD-L1 in THP-1 cells in each group. (C) Protein indexes and statistics of P-STAT3, PD-L1 in A549 cells in each group. (*P < 0.05; **P < 0.01).