Research Paper Volume 16, Issue 17 pp 12252—12262

Upregulation of EFCAB7 after radiofrequency ablation promoting hepatocellular carcinoma metastasis and survival by regulating PARK7

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Figure 1. EFCAB7 was upregulated after RFA and was associated with poor prognosis in HCC. (A, B) RT-PCR analysis of EFCAB7, APC, FAS, HGF and PCNA in HCC tumor tissues and adjacent tissues before and after RFA; (C) Expression of EFCAB7 in TCGA database; (D) Kaplan-Meier analysis demonstrated that HCC patients with low EFCAB7 expression had a better overall survival rate than patients with high EFCAB7 expression. Student’s t-test and log-rank test (*P < 0.05, **P < 0.01, ***P < 0.001).