Research Paper Volume 16, Issue 17 pp 12239—12251
MTA2 knockdown suppresses human osteosarcoma metastasis by inhibiting uPA expression
Figure 4. Effect of uPA treatment on migratory and invasive capabilities in human MTA2-depleted osteosarcoma cells. Treatment with or without Rh-uPA (200 ng/mL) in shLuc and shMTA2 osteosarcoma cells for 24 h, followed by the assessment of cell migration and invasion ability using the in vitro Boyden chamber migration and invasion assay. ** P < 0.01, compared with shLuc cells; # P < 0.05, compared with shMTA2 cells.