Research Paper Volume 16, Issue 16 pp 11939—11954

Identification of immunity- and ferroptosis-related signature genes as potential design targets for mRNA vaccines in AML patients

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Figure 6. Immune characteristics of the AML subtypes. (A, B) The expression levels of the six genes in the TCGA-LAML and GSE71014 cohorts based on the ssGSEA calculations. (C, D) The differences in immune cells and immune functions between the high- and low-risk groups revealed that the high-risk group had more immune cells than the low-risk group for most of the immune cell types. Only two types of immune cells, macrophages, and mast cells, were more common in the low-risk group than in the high-risk group. The high-risk group was found to have greater immune function than the low-risk group.