Research Paper Volume 16, Issue 16 pp 11939—11954

Figure 3. Identification of the ferroptosis-related genes. (A) Differential gene screening revealed a total of 5668 upregulated genes and 5316 downregulated genes based on the threshold. (B) By taking the intersection, 856 genes were identified as candidate genes for subsequent analysis. (C) Accumulation of TMB in each patient. (D, E) To establish scale-free networks, the soft thresholding power was set to β=6 based on scale independence and mean connectivity. (F, G) The dynamic tree cut package was used to generate a gene cluster dendrogram containing 6 coexpression models. (H) The coexpression models are shown in blue, turquoise, brown, green, yellow, and gray and contain 146, 218, 128, 70, 81, and 43 genes, respectively. p <0.05 was considered to indicate a significant module-trait relationship between the TMBRGs and vital status.