Research Paper Volume 16, Issue 16 pp 11904—11916

Figure 2. miR-432-5p alleviates ADR-caused cardiomyocytes injury. (A) The relative level of miR-432-5p in primary cardiomyocytes treated with ADR; (B) The relative level of miR-432-5p in ADR-treated mice; (C) The miR-432-5p mimic was transfected to primary cardiomyocytes, RT-PCR was performed to confirm the successful of transfection; (D–G) The increasing of miR-432-5p improved the cell viability caused by ADR; decreased ROS, IL-1β, and LDH levels in ADR treated cells. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.