Research Paper Volume 16, Issue 16 pp 11893—11903
Notch1 signaling pathway promotes growth and metastasis of gastric cancer via modulating CDH5
Figure 5. Overexpressed Notch1 promoted gastric cancer cell growth, invasion and migration with CDH5 involvement. (A) EdU assay in MGC-803 and HGC-27 cells transfected with NC, Notch1-lentivirus, and Notch1-lentivirus+si-CDH5. (B) Transwell assay in MGC-803 and HGC-27 cells transfected with NC, Notch1-lentivirus, and Notch1-lentivirus+si-CDH5. (C) Scratch wound healing assays in MGC-803 and HGC-27 cells transfected with NC, Notch1-lentivirus, and Notch1-lentivirus+si-CDH5. (D) Tubule formation assays in MGC-803 and HGC-27 cells transfected with NC, Notch1-lentivirus, and Notch1-lentivirus+si-CDH5.