Research Paper Volume 16, Issue 16 pp 11893—11903

Notch1 signaling pathway promotes growth and metastasis of gastric cancer via modulating CDH5

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Figure 2. CDH5 expression was upregulated in gastric cancer tissues. (A) Expression level of the CDH5 gene in the GC samples compared to normal tissues through GEPIA. (B) Representative photomicrographs of IHC staining show CDH5 expression in gastric cancer tissues and adjacent normal breast tissues in tissue microarrays. Magnification×40 (left) and ×100 (right). (C) The difference in CDH5 expression levels between GC tissues and adjacent tissues in tissue microarrays. (D) The difference in mRNA expression levels of CDH5 between GC tissues and adjacent tissues form 32-pair clinical tissue samples. **** P<0.0001.