Figure 4 — Circ_0006476 modulates macrophage apoptosis through the miR-3074-5p/DLL4 axis: implications for Notch signalling pathway regulation in cardiovascular disease

Research Paper|Volume 16, Issue 16|pp. 11857–11876

Circ_0006476 modulates macrophage apoptosis through the miR-3074-5p/DLL4 axis: implications for Notch signalling pathway regulation in cardiovascular disease

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Figure 4.Construction of the circRNA-miRNA–mRNA regulatory network in apoptotic cells. (A) circRNA-miRNA regulatory network. (B) miRNA–mRNA regulatory network. (C) Intersection of miRNA targets of circRNAs and mRNAs. (D) ceRNA regulatory network. (E) ceRNA regulatory network targeting DLL4. (F) GSEA of genes related to the notch signalling pathway.