Research Paper Volume 16, Issue 15 pp 11626—11655

Causal role of blood metabolites in HER-positive and HER-negative breast cancer: a Mendelian randomization (MR) study

class="figure-viewer-img"

Figure 4. (A) Venn diagram showed the intersection of blood metabolites that are causally involved in HER+ and HER-breast cancers. (B) Forest plots showed the causal associations between blood metabolites (Gamma-glutamyl glutamate levels and X-12849 levels) and HER+ breast cancer by using different methods. (C) Forest plots showed the causal associations between blood metabolites (Gamma-glutamyl glutamate levels and X-12849 levels) and HER- breast cancer by using different methods. Abbreviations: SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval.