Research Paper Volume 16, Issue 15 pp 11491—11500

Disease progression in Parkinson’s disease patients with mild cognitive impairment: 5-year longitudinal study from the early Parkinson’s disease longitudinal Singapore (PALS) cohort

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Figure 3. Cognitive progression between PD-MCI and PD-NC. (A) Progression slopes of MoCA score in PD-MCI and PD-NC group were -0.36 vs. -0.21, p=0.21. (B) Progression slopes of standardised visuospatial score in PD-MCI and PD-NC group were -0.13 vs. -0.06, p=0.048. Longitudinal linear mixed model was performed to compare the progression slopes of cognitive outcomes between PD-MCI and PD-NC group; analysis has been adjusted for age of diagnosis, sex and education year. Abbreviations: MoCA score: Montreal Cognitive Assessment score.