Research Paper Volume 16, Issue 15 pp 11491—11500
Disease progression in Parkinson’s disease patients with mild cognitive impairment: 5-year longitudinal study from the early Parkinson’s disease longitudinal Singapore (PALS) cohort
Figure 2. Non-motor progression between PD-MCI and PD-NC. (A) Progression slopes of NMSS total score in PD-MCI and PD-NC group were 3.74 vs. 2.06, p=0.14. (B) Progression slopes of NMSS domain 4 score in PD-MCI and PD-NC group were 0.38 vs. -0.04, p=0.01. Longitudinal linear mixed model was performed to compare the progression slopes of non-motor outcomes between PD-MCI and PD-NC group; analysis has been adjusted for age of diagnosis, sex and education year. Abbreviations: NMSS: non-motor symptom scale; NMSS domain 4 (perceptual problems/hallucinations).