Research Paper Volume 16, Issue 13 pp 11103—11116

HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis

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Figure 1. High expression of HOXC4 was observed in PC tissues and predicted poor outcome. (A, B) HOXA10 was highly expressed in PC tissues and associated with lower overall survival days. (C, D) HOXB7 was highly expressed in PC tissues and associated with lower overall survival days. (E, F) HOXC4 was highly expressed in PC tissues and associated with lower overall survival days. (G) qRT-PCR was used to detect the expression of HOXA10, HOXB7 and HOXC4 in PC tissues and adjacent tissues. (H) Pair analysis indicated that 53.5% PC patients had increased expression of HOXC4. (I) Diagnostic value of HOXC4 in PC. (J) IHC was used to detect the expression of HOXC4 in PC tissues and adjacent tissues. (K) KM plot indicated the survival days of PC patients with high and low HOXC4 expression. *P < 0.05; **P < 0.01.