Research Paper Volume 16, Issue 13 pp 11090—11102
LIMK1 promotes the development of cervical cancer by up-regulating the ROS/Src-FAK/cofilin signaling pathway
Figure 6. LIMK1 induced oxidative stress in cervical cancer cells, inhibited p-SHP2 and promoted the expression of p-Src, p-FAK, p-ROCK1/2, and p-Cofilin-1. (A) Effects of LIMK1 on the expression of NOX2, NOX4, p-Src, p-FAK, p-ROCK1/2, p-Cofilin-1, F-actin and p-SHP2 proteins in cervical cancer cells. (B) Statistical analysis bar chart of Western blotting. **P<0.01 indicated statistically significant differences.