Research Paper Volume 16, Issue 13 pp 11090—11102

Figure 1. Raw letter analysis results. (A) Volcano plot of visualized grouped differential genes (DEGs) for dataset GSE173097 was constructed in R software using the ggplot2 package; (B) heatmap of cluster analysis of DEGs was plotted using the R package pheatmap; (C) biological processes containing the top 10 counts were plotted in the R language environment using GOplot as well as the ggplot2 package, cellular components and molecular functions of up-regulated differentially expressed genes in GO pathway pathway maps; (D) enrichment in biological processes such as inflammatory response, signal transduction, G-protein coupled receptor signaling pathway chordal maps; (E) GO pathway maps containing differentially expressed genes down-regulated by BP, CC, and MF; (F) enrichment in negative regulation of transcription from RNA polymerase II promoter, proteolysis, negative regulation of cell proliferation and other biological processes; (G) KEGG enrichment analysis; (H) box plot of expression in diseased and normal tissues; (I) LIMK1 prognostic overall survival curves; (J) LIMK1 and SOD1 plotted as a correlation scatterplot; (K) sod1 and SRC plotted as a correlation scatterplot; (L) PTPN1 and SRC plotted as a correlation scatter plots.