Figure 5 — Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway

Research Paper|Volume 16, Issue 13|pp. 11062–11071

Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway

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Figure 5.Sevoflurane could relieve calcium influx and ER stress. (A) Protein bands of p-PLCγ, p-CaMKII, p-IP3R, GRP78 and GRP94 in Sham group, Model group and Sevoflurane group, (B) relative protein expressions of p-PLCγ, p-CaMKII, p-IP3R, GRP78 and GRP94 in Sham group, Model group and Sevoflurane group. Sham group vs. Model group, Model group vs. Sevoflurane group, Control group vs. Sevoflurane group, **P<0.01, N=8.