Research Paper Volume 16, Issue 18 pp 12510—12524

LncRNA DANCR promotes macrophage lipid accumulation through modulation of membrane cholesterol transporters

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Figure 2. The expression of DANCR is increased in ox-LDL-treated human THP-1 macrophages and mouse RAW264.7 macrophages. (A, B) THP-1 cells were incubated with 160 ng/mL PMA for 48 h to differentiate into macrophages. Then, THP-1-derived macrophages or RAW264.7 macrophages were treated with 50 μg/mL ox-LDL for 24 h. qPCR was used to detect the expression of DANCR. All results are presented as the mean ± SD from three independent experiments performed in triplicate. n=3.