Research Paper Volume 16, Issue 13 pp 10972—10984

Unveiling diabetic nephropathy: a novel diagnostic model through single-cell sequencing and co-expression analysis

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Figure 4. Identification of key disulfidptosis-related genes in DN. (A) Intersection analysis identifying 21 critical genes related to disulfidptosis in DN through single-cell analysis, differential expression, and WGCNA. (B) Protein interaction network analysis highlighting MAGI2 as a central factor in gene-gene interactions. (C, D) Functional enrichment analysis of the 21 key genes, showing significant association with receptor internalization and MAPK signaling pathway.