Figure 6. Novel CD8+ T cell clusters under immune escape related gene modifications. (A) Differential gene expression analysis (DEGs) unveiled sets of genes exhibiting positive and negative correlations with the five subtypes of CD8+ T cells. (B) Enrichment of immune escape related signaling pathways in CD8+ T cell clusters was shown by bubble diagram. (C) Heat map demonstrating immune escape related CD8+ T cell clusters enriched in a characteristic subpopulation of previous CD8+ T cells. (D) Transcription factor activities of immune escape related CD8+ T cell clusters are shown by heat maps.