Figure 5. Novel CD8+ T cell clusters under immune escape related gene modifications. (A, B) UMAP showed CD8+ T cell clusters after immune escape related gene annotation. (C) Cell percentages showed expression of novel fibroblast clusters in 13 CRC patients. (D) Cell chat revealed the interaction of novel CD8+ T cell clusters with kinds of cells. (E) The signaling pathways of the novel CD8+ T cell cluster inputs and outputs were shown by heat map. (F) Trajectory analysis reveals the role of immune escape related genes in CD8+ T cell clustering after NMF classification.