Research Paper

Single-cell immune escape correlation analysis: unraveling the prognostic influence of intercellular communication in the tumor microenvironment of colorectal cancer

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Figure 4. Novel fibroblast clusters under immune escape related gene modifications. (A) Differential gene expression analysis (DEGs) unveiled sets of genes exhibiting positive and negative correlations with the four subtypes of CAF cells. (B) Enrichment of immune escape related signaling pathways in fibroblast clusters was shown by bubble diagram. (C) Heat map demonstrating immune escape related fibroblast clusters enriched in a characteristic subpopulation of previous fibroblasts. (D) Transcription factor activities of immune escape related fibroblast clusters are shown by heat maps.