Research Paper
Single-cell immune escape correlation analysis: unraveling the prognostic influence of intercellular communication in the tumor microenvironment of colorectal cancer
Figure 3. Novel fibroblast clusters under immune escape related gene modifications. (A, B) UMAP showed fibroblast clusters after immune escape related gene annotation. (C) Cell percentages showed expression of novel fibroblast clusters in 12 CRC patients. (D) Cell chat revealed the interaction of novel fibroblast clusters with kinds of cells. (E, F) The signaling pathways of the novel fibroblast cluster inputs and outputs and the GAS signaling pathway network were shown by heat map. (G) Pseudo time showed the differentiation of fibroblast clusters after NMF classification. (H) Trajectory analysis reveals the role of immune escape related genes in fibroblast clustering after NMF classification.