Research Paper Volume 16, Issue 15 pp 11535—11552
Exploring the mechanism by which Angelica sinensis improves haematopoietic function in aplastic anaemia
Figure 9. The mechanism summary diagram. AS and ASP could downregulate the expression of IL17A, and inhibit the activation of p38/MAPK pathway induced by abnormal cytokines and ROS, thereby ameliorating the aberrant levels of Bad, Bax and Bcl-2, and rectifying the abnormal apoptosis of bone marrow hematopoietic stem cells.