Research Paper Volume 16, Issue 15 pp 11535—11552
Exploring the mechanism by which Angelica sinensis improves haematopoietic function in aplastic anaemia
Figure 8. Effects of ASP on apoptosis in vitro. (A) BMNC cell viability was tested in vitro. (B) Markers of Bcl-2/Bax pathway apoptosis and the p38/MAPK signaling pathway were tested using Western blotting in BMNC cells. (C) Markers of Bax-associated mitochondrial apoptosis pathway were tested after treated with medium dose ASP. (D) The colocalization of Bax with mitochondria (yellow dots). (E) Mitochondrial structure was detected by electron microscopy. Note: *P < 0.05 and **P < 0.01 compared with the normal control group. ▲P < 0.05 and ▲▲P < 0.01 compared with the model control group.