Figure 8.Effects of ASP on apoptosis in vitro. (A) BMNC cell viability was tested in vitro. (B) Markers of Bcl-2/Bax pathway apoptosis and the p38/MAPK signaling pathway were tested using Western blotting in BMNC cells. (C) Markers of Bax-associated mitochondrial apoptosis pathway were tested after treated with medium dose ASP. (D) The colocalization of Bax with mitochondria (yellow dots). (E) Mitochondrial structure was detected by electron microscopy. Note: *P < 0.05 and **P < 0.01 compared with the normal control group. ▲P < 0.05 and ▲▲P < 0.01 compared with the model control group.
