Research Paper Volume 16, Issue 15 pp 11535—11552

Figure 6. Assessment of the ASP treatment in the AA mice. (A) Peripheral blood cell counts in the different groups. (B) BMNC counts assay in the different groups. (C, D) Hematopoietic tissue assay and bone marrow biopsy of different mice groups on day 14 (×400). (E) Treg and Th17 cells were detected using FCM. (F) The Treg/Th17 ratio in different AA groups. (G) The levels of IL-17A and TGF-β in different groups. (H) Immunofluorescence images of ROS. (I) The ROS levels of each group were assessed. Note: ^*P < 0.05 and ^**P < 0.01 compared with the normal control group. ^▲P < 0.05 and ^▲▲P < 0.01 compared with the model control group, ^#P < 0.05 and ^##P < 0.01 compared with the low-dose group.