Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis

Nailin Zhang; Pingping Chen; Xiaoyan Liang; Jianhui Sun; Qiquan Liu; Shengjiang Guan; Qiao Wang

doi:doi:10.18632/aging.205969

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Research Paper Volume 16, Issue 13 pp 10918—10930

Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis

Figure 3. Luteolin has a therapeutic effect on rat CAG in vivo. (A) CAG animal modeling and treatment flowchart. (B) Top view of the rat gastric tissue anatomy. (C) Body weight curves of the rats. (D) HE staining of rat gastric tissues. CAG, chronic atrophic gastritis; HE, hematoxylin and eosin.