Research Paper Volume 16, Issue 13 pp 10882—10904
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure
Figure 9. Correlation between intestinal flora and inflammatory cytokines in the hippocampus. (A) The linear discriminant analysis effect size (LEfSe) analysis at species level between Sham and CHF groups. (B) The top 10 species sorted by the relative abundance alterations between Sham and CHF groups. (C) Spearman analysis correlating differential flora and biochemical indicators of cardiac function, inflammatory cytokines, BDNF and key hippocampal proteins in the hippocampus. Data are presented as the Mean ± SEM; *P < 0.05, and **P < 0.01 vs. Sham; n = 6.