Research Paper Advance Articles
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure
Figure 4. CHF causes the loss of Nissl bodies and ultrastructural damage of neurons in the hippocampus. (A) Representative images of Nissl’s staining. (B–D) Quantifications of Nissl bodies in CA1, CA3, DG regions in the hippocampus, respectively n = 4. (E) Representative ultrastructural images of neurons shown at magnifications of ×2500, scale bars: 20 μm; ×8000, scale bars: 5 μm. Data are presented as the Mean ± SEM; *P < 0.05, and **P < 0.01 vs. Sham; n = 3.