Research Paper Advance Articles

Figure 1. The cardiac function and hemal physiological and biological indices in CHF rats. (A) Animal experiment timeline. (B) Representative electrocardiograms at 24 hours before and after surgery. (C–E) Representative M mode echocardiograms of Sham and CHF rats (C) and quantifications of left ventricular ejection fraction (LVEF) (D), left ventricular fraction shortening (LVFS) (E). (F–I) Quantifications of cardiac hemodynamic parameters, including left ventricular systolic pressure (LVSP) (F), left ventricular end-diastolic pressure (LVEDP) (G), +dp/dtmax (H), −dp/dtmax (I). (J–N) The BNP (J), NT-proBNP (K), cTnT (L), sST2 (M) and Ang II (N) levels in serum were measured by ELISA. Data are presented as the Mean ± SEM; ^*P < 0.05, and ^**P < 0.01 vs. Sham; n = 8.